Interestingly, stathmin is reported to be associated with the expression of VEGF and hypoxia-inducible factor a (HIF-1a).12 VEGF is well known as an important cytokine in the pathogenesis of POEMS syndrome.13 In AL amyloidosis, the expression of the lambda light chain (IGLL1) gene was significantly elevated; however, we could not confirm this result via qPCR (Supplementary Figure S1). This evidence concerns the gene VEGFA and POEMS syndrome.