The active forms of MARCKS are phosphorylated on serine residues by PKC12 mediating the oncogenic effects.13 This contention is supported by another study demonstrating that phosphorylation of MARCKS mediates cancer invasiveness14 in a PKC-dependent manner.15 We therefore investigated the abundance of two previously tested residues, phosphoMARCKS (pMARCKS)Ser162 and pMARCKSSer159/163, in MCL and CLL. Here, MARCKS is linked to mantle cell lymphoma.