MARCKS and B-cell chronic lymphocytic leukemia: As expected, MARCKS is a predicted target of several microRNAs using the DIANA Tools (http://diana.imis.athena-innovation.gr/DianaTools/index.php?r=site/page&view=software), and among them also of miR-155 (that is differentially expressed between MCL and CLL) with three 12 nt homologies based on miRanda predictions.5 As expected, a trend to a negative correlation between miR-155 and MARCKS was observed in CLL (r=−0.418), but not in MCL (r=0.046; Supplementary Figure S5), suggesting that miR-155 inhibits MARCKS expression in CLL.