Some antigens (CD23 and CD200) are expressed in CLL, however, not in all cases.2 In addition, few CLL cases also contained the t(11;14) translocation.3 Overlapping and disease-specific features are not always reliable to distinguish between MCL and CLL, and this requires identification of additional biomarkers. This evidence concerns the gene FCER2 and B-cell chronic lymphocytic leukemia.