As shown in Figure 3D–3F, tumors with PON3 overexpression (HCC-LM3-PON3) showed a significantly decreased tumor growth compared with its control (HCC-LM3-NC), reflected by tumors' volume and weight (p = 0.046 for tumor volume, p = 0.021 for tumor weight). Here, PON3 is linked to hepatocellular carcinoma.