IGF-IR is preferentially expressed in T-ALL cell linesMicroRNA-223 decreases IGF-IR expression in T-ALLMicroRNA-99a and microRNA-100 overexpression inhibits the expression of IGF-IR and mTOR, as well as downstream proteins MCL-1 and FKBP51 in T-ALL. The gene discussed is IGF1R; the disease is acute lymphoblastic leukemia.