MOS and age-related macular degeneration: The activation of Mos significantly prolonged their survival in contact with porcine and human RPE cells similar to AMD where MPs are observed on the apical side of RPE cells around geographic atrophy lesions, subretinal neovascularization, and large drusen (Gupta et al., 2003; Combadière et al., 2007; Lad et al., 2015; Levy et al., 2015a).