We also performed real-time PCR in 4 normal ovarian tissues and 17 of the 75 clear cell carcinomas (Supplementary Figure 3A), and found that MDM2 expression was significantly higher in clear cell carcinomas than in normal ovaries (P = 0.039) (Supplementary Figure 3A), and that the expression level of MDM2 determined by microarray was highly associated with that determined by real-time PCR (Supplementary Figure 3B). Here, MDM2 is linked to clear cell adenocarcinoma.