Analysis of CD44+CD24lo cells in human colon carcinoma cell lines indicated that six of eight human colon carcinoma cell lines contain a subset of CD44+CD24lo cells (Supplementary Figure S4A & S4B), and the majority of CD44+CD24lo cells are also CD133+CD24lo cells (Supplementary Figure S4C). The gene discussed is PROM1; the disease is colon carcinoma.