First functional data highlight the role of miR-134-5p, miR-432-5p and miR-433-3p in the modulation of EGFR protein levels in 2A and 5C AI resistance models, a finding that is in line with the recently reported direct targeting of the EGFR 3′UTR sequence by miR-134-5p in non-small cell lung cancer cell models [45]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.