Subsequently, we tested also the effect of STAT3 inhibition on cell proliferation and apoptosis pre-incubating LCLs with 20 μM STAT Three Inhibitory Compound (STATTIC), which has been recently reported to induce apoptosis and block cell proliferation in prostate and colon cancer cells39, 40. The gene discussed is STAT3; the disease is malignant colon neoplasm.