As a master regulator of pro-inflammatory cytokines such as IL-1β, IL-6 and GM-CSF [2], over expression of TNF-α causes a variety of chronic inflammatory diseases including rheumatoid arthritis, Crohn’s disease, psoriatic arthritis, ankylosing spondylitis and psoriasis, and so on [3]. Here, IL6 is linked to rheumatoid arthritis.