VIM and squamous cell carcinoma: In this present meta-analysis, we demonstrated that the overexpression of vimentin predicted a poor overall survival of NSCLC in the univariate analysis and up-regulated vimentin expression was associated with several clinicopathological factors, including histology of squamous cell carcinoma, smoking, poor differentiation, advanced TNM stages, vascular invasion, lymph node metastasis and recurrence in NSCLC.