Immunehistochemical staining showed that the expression of P65 increased by E44 infection in wildtype mice was decreased in both vimenin -/- mice and ZD1 infection in the brain cortex (Fig 2A), especially the BBB indicated by endothelial cells, which form the microvascular blood vessels (Fig 2B), as well as hippocampal CA1 (S2A Fig) and dentate gyrus (S2B Fig). Here, RELA is linked to zygodactyly type 1.