Interestingly, patient 5 showed a reduction in total LC3B protein content (both LC3B-I and -II) after the LPD (Fig. 1A), although the corresponding transcript was induced with respect to the baseline condition (T0) (Fig. 1C), suggesting the possibility that in this patient LC3B protein was degraded by sustained autophagy flux. This evidence concerns the gene MAP1LC3B and disseminated peritoneal leiomyomatosis.