CF patients bearing class II mutations, including ΔF508, could benefit from correctors treatment, since these CFTR mutants fail to reach complete folding and the ER machinery targets the protein to be degraded (Van Goor et al., 2006; Atawade et al., 2015; Rapino et al., 2015; Lopes-Pacheco et al., 2016). This evidence concerns the gene CFTR and cystic fibrosis.