2007; Ricart et al. 2011). Additionally, Ramkhelawon et al. (2014) recently demonstrated that HFD feeding impairs CCR7‐mediated ATM chemotaxis due to elevated netrin‐1 expression. Preventing netrin‐1 signaling in ATMs via adoptive transfer of Ntn1−/− fetal liver cells, increases ATM emigration to draining lymph nodes, suggesting that CCR7 remains a viable target for altering ATM accumulation in obesity. This evidence concerns the gene NTN1 and obesity due to melanocortin 4 receptor deficiency.