HCST and B-cell chronic lymphocytic leukemia: However, NKG2D is expressed as a dimer associated with the adaptor protein DAP10 [19, 20] and expression of the HCST gene, which encodes DAP10 was markedly reduced in CLL- NK cells compared with HD-NK and SLL-NK (mean transcription: HD-NK 240 vs CLL-NK 162 vs SLL- NK 428 respectively) (Figure 5A).