IGF2BP1 and metastatic neoplasm: MMTV-PYMT mice without the IMP1 transgene and MMTV-PYMT-IMP1 mice without induction of the IMP1 transgene by doxycycline developed either gross or histological pulmonary metastatic disease (Figure 4C &4Dn = 7 mice, n = 7 lung sections).