MMTV-PYMT-IMP1 mice (n = 7) with doxycycline induction developed mammary tumors but showed few or no lung metastasis (n = 7 mice, 7 lung sections Figure 2B and 2H & 2E stain of a representative lung section in Figure 2C & 2D). The gene discussed is IGF2BP1; the disease is breast cancer.