Doxycycline treated IMP1-GFP mice without the MMTV-PYMT transgene (n = 22 mice) did not develop mammary tumors within the observation period (8 weeks) whereas all MMTV-PYMT transgenic mice with or without the IMP1 transgene induction developed multiple mammary gland masses (n = 18 mice). Here, IGF2BP1 is linked to breast cancer.