Multivariate analysis on IDH1-R132H expression, differentiation, tumor stage, preoperative CA19-9 level, and CEA level revealed that low IDH1-R132H expression (HR, 0.587, P=0.019), tumor stage (HR, 1.533, P<0.001), and preoperative CEA (HR, 2.432, P<0.001) correlated with poor OS (Table 4). Here, IDH1 is linked to neoplasm.