In many published studies, a wide range in the prevalence of EGFR mutations has been reported in lung carcinomas, from 7.5 % in Norway [23, 24], 8.8 % in a mixed ethnic population in the USA [10], to 10 to 15 % in Europe [20, 22], to more than 50 % in Asian countries [25, 26]. This evidence concerns the gene EGFR and lung carcinoma.