FOXC2 and non-small cell lung carcinoma: The current study suggested that COX-2 upregulates β1-integrin expression and cell invasion in NSCLC cells through the Prostaglandin E Receptor EP1, and the PKC/MAPK/E2F-1/FoxC2 signalling pathway might be involved in COX-2-mediated β1-integrin upregulation.