Meanwhile, dietary Se deprivation exacerbated hair graying and alopecia (scored 4+; 9–18 months, 32% vs. 9%; > 18 months, 50% vs. 18%; Figs 2A and S5A), cataract formation (Fig. 2B) and spontaneous skin lesion (Fig. S5B), delayed healing of acute wounds on skin (Fig. 2C), and lowered femoral conductivity (Fig. 2D) as the male G3 Terc−/− mice aged. Here, TERC is linked to alopecia.