Saunders et al. 12 however identified T memory cells by using CD45RO expression, and found increased CD4+ T memory cells only in PD patients with UPDRS Part III score ≥31, while in our study we enrolled only 7 patients with a score above 20, the highest score being 24, and nonetheless we identified increased TEM in PD patients, possibly also thanks to the specific flow cytometry staining strategy which included the expression of CD45RA and CCR7, and allowed to distinguish between TEM and TCM28. The gene discussed is CCR7; the disease is Parkinson disease.