Our results show that mRNA expression of several DR are dysregulated in CD4+ T cells from PD patients: in particular, in comparison to cells from HS, in cells from PD patients mRNA for the D1-like DR D5 and for the D2-like DR D3 and D4 are decreased, and mRNA for the D2-like DR D3 is increased (Fig. 2a,b). Here, CD4 is linked to Parkinson disease.