Flow cytometric analysis of DR expression on CD4+ T cells revealed that in PD patients DR D5+ CD4+ T cells were decreased in terms of both absolute number and percentage of total CD4+ T cells (Fig. 2c,e), and that PD-dn patients had lower number and percentage of DR D1+ and D3+ CD4+ T cells in comparison to PD-dt subjects (Fig. 2d,f). The gene discussed is CD4; the disease is Parkinson disease.