GPT and Decreased liver function: Four clinical trials (Hézode et al. 2015; Dore et al. 2015; Suzuki et al. 2014; Izumi et al. 2014) mentioned the effect of daclatasvir on the liver function, which included elevated alanine aminotransferase (ALT), elevated total bilirubin (TBil), etc. Meta-analysis results indicated that there were no significant differences in the liver dysfunction between daclatasvir and control groups (p > 0.05, Table 3).