TLR4 and coronary artery disorder: With the use of SNPs as molecular markers, many genetic association studies were performed to investigate the associations of TLR4 gene polymorphisms with the risk of CAD (Kolek et al. 2004; Balistreri et al. 2004; Incalcaterra et al. 2010; Zee et al. 2005; Koch et al. 2006; Nebel et al. 2007; Džumhur et al. 2012).