TLR4 and coronary artery disorder: Some of them showed that TLR4 gene polymorphisms were associated with a lower risk of CAD (Kolek et al. 2004; Balistreri et al. 2004; Incalcaterra et al. 2010), while the others found no relationship between them (Zee et al. 2005; Koch et al. 2006; Nebel et al. 2007; Džumhur et al. 2012).