INS and Glucose intolerance: Furthermore, an oral glucose tolerance test and hyperinsulinemic euglycemic clamp revealed the absence of glucose intolerance (area under the curve was 1823 ± 156 versus 1549 ± 68 in control mice, p = 0.13) and whole body insulin resistance (glucose infusion rate during hyperinsulinemic clamp was 24 ± 3 in WD-fed mice versus 25 ± 2 mg/min/kg in control mice, p = 0.73).