Using 14055 probes that showed expression above the background, we established an ETV6/RUNX1-specific lncRNA signature consisting of 596 lncRNA transcripts (434 up- and 162 down-regulated) that showed significant differential expression between ETV6/RUNX1-positive BCP-ALL and other genetic BCP-ALL subclasses (adj. The gene discussed is ETV6; the disease is acute lymphoblastic leukemia.