Incubation with CPZ (5  μM) or SKF (5 μM) before each individual application of 420 nm and 540 nm photobiomodulation delivered 5 times over 21 days, significantly decreased RUNX2, OSX, and OCN expression levels as compared to the control group (OM alone) (Fig. 4A–C). Here, SP7 is linked to ocular melanoma.