Following further re-categorization,39 when compared with the middle tertile, the odds ratios (95% confidence interval) of depression for the lowest and highest tertiles of IGF-1 among men were 1.14 (0.72, 1.80) and 0.89 (0.55, 1.43), respectively, and corresponding results for women were 1.08 (0.79, 1.49) and 1.14 (0.79, 1.65). Here, IGF1 is linked to depressive disorder.