G6PD activity per see can cause deleterious changes in cellular functions.3 An experimental study proved that the G6PD enzyme deficient mouse model is stimulating an inflammatory reaction in the kidney leading to an alteration in metabolic processing of albumin by the kidney tubules.30 G6PD, which is an indispensable component of antioxidant defense, plays pathogenic roles in diseases other than hemolytic disorders and may play a major role in the pathogenesis of the unexplained kidney diseases.4 Here, G6PD is linked to kidney disorder.