As shown in Fig. 2a-b, The percentage of early apoptotic tumor cells(AnnexinV-FITC positive, PI negative) in the combined treatment(35.06 % ± 6.98 %) was significantly higher than that with radiation (16.73 % ± 4.52 %) or chloroquine(6.94 % ± 1.21 %) alone. The gene discussed is ANXA5; the disease is neoplasm.