Our previous studies [45]; suggested that the development of AMD-CNV may have a common genetic origin with mCNV, but we did not find a significant association between two-single nucleotide polymorphisms (SNPs) strongly associated with AMD (rs1061170 [Y402H] in CFH and rs10490924 [A69S] in ARMS2) and myopic CNV in a Spanish population. The gene discussed is ARMS2; the disease is age-related macular degeneration.