As shown in Table 1, upregulation of SPRY4‐IT1 was markedly correlated with tumor size, FIGO stage, SCC‐Ag, and lymph node metastasis (P < 0.05), but not correlated with patient's age and histology (P > 0.05). Here, SPRY4 is linked to metastatic malignant neoplasm in the lymph nodes.