The group of Connie Eaves presented a preleukemic in vivo model for CML by transducing primary human cord blood CD34+ cells with MSCV driven p210 BCR-ABL followed by transplantation into NOD-SCID and NOD-SCID β2−/− mice. This evidence concerns the gene EVPL and chronic myelogenous leukemia, BCR-ABL1 positive.