The group of Connie Eaves presented a preleukemic in vivo model for CML by transducing primary human cord blood CD34+ cells with MSCV driven p210 BCR-ABL followed by transplantation into NOD-SCID and NOD-SCID β2−/− mice. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.