CEACAM1 and melanoma: In vitro and in vivo studies on melanoma xenografts show that antibodies built to target the extracellular portion of CEACAM1 and to block the N-domain of CEACAM1 (MRG1, a murine IgG1 monoclonal antibody against human CEACAM1) did not influence the proliferation rate but facilitate melanoma cell elimination by T cells and have no agonistic effect.