In the last decades cancer therapy studies have focused on targeted molecular treatments (monoclonal antibody, small molecule tyrosine kinase inhibitor); therefore scientists have developed a great interest for EGFR (epidermal growth factor receptor) which is a tyrosine kinase receptor and two of its most important ligands are epidermal growth factor and transforming growth factor-α and its roles are skin cell proliferation and differentiation, thus contributing to tumorigenesis [57–59]. This evidence concerns the gene EGFR and cancer.