At a cutoff value of 21, poorly differentiated adenocarcinoma was successfully distinguished from moderately and well-differentiated adenocarcinomas with high levels of sensitivity and specificity (Table 1b), indicating that nuclear localization of tricellulin in poorly differentiated pancreatic adenocarcinoma is significantly different from that in moderately and well-differentiated adenocarcinomas. This evidence concerns the gene MARVELD2 and pancreatic adenocarcinoma.