In humans, ADAMTS18 mutations are associated with pleomorphic ocular manifestations, including microcornea, ectopic pupils, childhood cataract, night blindness, ectopia lentis, rhegmatogenous retinal detachment, and cone-rod dystrophy (Aldahmesh et al., 2013; Peluso et al., 2013; Chandra et al., 2014). This evidence concerns the gene ADAMTS18 and Rod-cone dystrophy.