IFNG and neoplasm: Moreover, VEGF-A mRNA expression in the xenografts (Tumor IDs 1–8), which were from animals not treated with exogenous cytokines, reached levels similar to those found in vitro following IFN-γ exposure (BxPC-3-IFN-γ; BxPC-3 cells exposed to 25 ng/ml IFN-γ for 24 h).