DUOX2 and neoplasm: BxPC-3 cells treated with IFN-γ produced significantly more H2O2 over time compared to cells not incubated with IFN-γ (P < 0.001 at all times); and DPI treatment decreased DUOX2-mediated H2O2 release by the IFN-γ-stimulated tumor cells to near-basal levels.