Early after the booster, SLP vaccination resulted in the induction of a highly activated CD8+ T cell subset exhibiting an effector-like phenotype (CD62Llo, CD44hi, CD127lo, KLRG1hi), which completely resembled the MCMV-specific T cell phenotype during the acute phase of the infection (Fig 3A and 3B). The gene discussed is CD8A; the disease is infection.