CXCL12 is reported to play a critical role in neuroprotection after stroke, by recruitment of endothelial progenitor cells and neuronal progenitor cells in the subventricular zone (SVZ) [54, 65, 66] as well as by promoting proliferation, differentiation, and migration of those progenitor cells [55, 67]. This evidence concerns the gene CXCL12 and Stroke.