Analysis of the Broad Institute Cell Line Encyclopedia46 indicates that Ewing sarcoma is the fifth highest PARP-1-expressing malignancy and that expression is significantly higher than that of other solid bone sarcomas such as osteosarcoma (P = 0.0400) and chondrosarcoma (P = 0.0176) (Figure 2a). The gene discussed is PARP1; the disease is Ewing sarcoma.