We identified in multiple myeloma patients mobilized with G-CSF alone higher collection of autograft absolute lymphocyte count compared with multiple myeloma patients mobilized with G-SCF + Cytoxan chemotherapy (C + G-CSF: G-CSF = 0.764 × 109 lymphocytes/kg (range: 0.146–1.803) versus C + G-CSF of 0.212 × 109 lymphocytes/kg (range: 0.016–1.26), P < 0.0001. Here, CSF3 is linked to plasma cell myeloma.