Indeed, GOLPH3 was shown to be an independent prognosis indicator for 5 year-DFS (HR = 2.624; 95% CI 1.235–6.541, P = 0.009) and OS (HR = 2.354; 95% CI 1.237–6.152, P = 0.039) in rectal cancer (Table 5). The gene discussed is GOLPH3; the disease is rectal cancer.