Low tumor epithelial HIF-1α protein expression was more often observed in patients with non-endometrioid subtype, high histological grade, deep myometrial invasion, lymph node metastasis, high International Federation of Gynecology and Obstetrics (FIGO) stage and in tumors with loss of hormone receptors (Table 1, Figure 1A). The gene discussed is HIF1A; the disease is neoplasm.