Besides slightly different subtype and endpoint definitions, it must be considered that Broukhaert et al. used tumor grade instead of Ki-67 for defining subtypes, (with the associated problems mentioned above), and Minicozzi et al. studied a retrospective cohort (2003–2005) with a different Ki-67 cut-off and lack of reliable information about how Ki-67 was determined at that time. This evidence concerns the gene MKI67 and neoplasm.