Another protein with increased abundance in 2-day-old DMD vs. WT pigs was Xin actin-binding repeat-containing protein 1 (XIRP1), a multi-adaptor protein which plays important roles in the assembly and repair of myofibrils and is capable of binding filamin C (FLNC) and the dystrophin-binding protein aciculin (PGM5)52. The gene discussed is FLNC; the disease is Duchenne muscular dystrophy.