Interestingly, several cell motility-related genes, such as actin (Actb), actin related protein 2/3 complex (Arpc5 and Arpc1b), guanine nucleotide binding protein (Gna13), integrin (Itga2), neuroblastoma ras oncogene (Nras), platelet derived growth factor (Pdgfb), RAS-related C3 botulinum toxin (Rac1), GTPase activating protein (Iqgap1), myosin (Myh9) and WAS protein family (Was and Wasf2) were significantly up-regulated in the infection with the WT but absent in the infection with BM16 mutant. The gene discussed is IQGAP1; the disease is infection.