TAAR1 and Multiple Organ Failure: However, the length of ICU stay, the incidence of multiple organ failure (MOF) and duration of mechanical ventilation were not significantly affected by Tα1 treatment (SMD −0.52, 95 % CI −1.06 to 0.11, p = 0.06; SMD −0.49, 95 % CI −1.09 to 0.11, p = 0.11; SMD −0.37, 95 % CI −0.90 to 0.17, p = 0.17, respectively).