Also, 6AP & GA showed benefit in a Drosophila-based model of OPMD (Oculopharyngeal muscular dystrophy), an inherited dominant myodegenerative disease caused by extension of a polyalanine tract in PABPN1 protein resulting in amyloid fiber accumulation19. The gene discussed is PABPN1; the disease is oculopharyngeal muscular dystrophy.