PECAM1 and infection: To determine the cellular compartment responsible for chemokine production, we sorted cellular subsets from the tongue of naïve and C. albicans-infected mice on day 1 post-infection, the peak of the neutrophil response, including CD45+ leukocytes, CD45- EpCAM+ CD31- keratinocytes and CD45- EpCAM- CD31+ endothelial cells (S3 Fig) and analyzed chemokine expression at the transcriptional level.